2008.09-2012.07 中国药科大学 药学（药物化学）
2012.09-2019.02中国科学院上海有机所生物与化学交叉中心

程序性细胞坏死的机制及小分子抑制剂

1. Meng, H., Liu, Z., Li, X., Wang, H., Jin, T., Wu, G., Shan, B., Christofferson, D.E., Qi, C., Yu, Q., et al. (2018). Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America 115, E2001-E2009.
2. Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J. TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging. Cell. 2018 09 06; 174(6):1477-1491.
3. Wang, H., Meng, H., Li, X., Zhu, K., Dong, K., Mookhtiar, A.K., Wei, H., Li, Y., Sun, S.C., and Yuan, J. (2017). PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proceedings of the National Academy of Sciences of the United States of America 114, 11944-11949.
4. Xu, D., Zhang, T., Xiao, J., Zhu, K., Wei, R., Wu, Z., Meng, H., Li, Y., and Yuan, J. (2015). Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy 11, 617-628.
5. Zhang, X., Li, X., Ye, S., Zhang, Y., Tao, L., Gao, Y., Gong, D., Xi, M., Meng, H., Zhang, M., et al. (2012). Synthesis, SAR and biological evaluation of natural and non-natural hydroxylated and prenylated xanthones as antitumor agents. Medicinal chemistry 8, 1012-1025.