2021:
(1-33)
1. Gu J, Wang C, Hu R, Li Y, Zhang S, Sun Y, Wang Q, Li D, Fang Y, Liu C. Hsp70 chaperones TDP-43 in dynamic, liquid-like phase and prevents it from amyloid aggregation. Cell Res 31: 1024-1027, 2021.
2. Xu G, Li Y, Zhang S, Peng H, Wang Y, Li D, Jin T, He Z, Tong Y, Qi C, Wu G, Dong K, Gou J, Liu Y, Xiao T, Qu J, Li L, Liu L, Zhao P, Zhang Z, Yuan J. SARS-CoV-2 promotes RIPK1 activation to facilitate viral propagation. Cell Res 2021.
3. Zhu G, Xie J, Fu Z, Wang M, Zhang Q, He H, Chen Z, Guo X, Zhu J. Pharmacological inhibition of SRC-1 phase separation suppresses YAP oncogenic transcription activity. Cell Res 2021.
4. Yang W, He H, Wang T, Su N, Zhang F, Jiang K, Zhu J, Zhang C, Niu K, Wang L, Yuan X, Liu N, Li L, Wei W, Hu J. Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice. Hepatology 74: 2774-2790, 2021.
5. Zhang K, Wang A, Zhong K, Qi S, Wei C, Shu X, Tu WY, Xu W, Xia C, Xiao Y, Chen A, Bai L, Zhang J, Luo B, Wang W, Shen C. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model. Neuron 109: 1949-1962 e1946, 2021.
6. Xu D, Zou C and Yuan J. Genetic Regulation of RIPK1 and Necroptosis. Annu Rev Genet 55: 235-263, 2021.
7. Zhang K, Jiang M and Fang Y. The Drama of Wallerian Degeneration: The Cast, Crew, and Script. Annu Rev Genet 55: 93-113, 2021.
8. Ni J, Ren Y, Su T, Zhou J, Fu C, Lu Y, Li D, Zhao J, Li Y, Zhang Y, Fang Y, Liu N, Geng Y, Chen Y. Loss of TDP-43 function underlies hippocampal and cortical synaptic deficits in TDP-43 proteinopathies. Mol Psychiatry 2021.
9. Liu D, Wei Q, Xia W, He C, Zhang Q, Huang L, Wang X, Sun Y, Ma Y, Zhang X, Wang Y, Shi X, Liu C, Dong S. O-Glycosylation Induces Amyloid-beta To Form New Fibril Polymorphs Vulnerable for Degradation. J Am Chem Soc 143: 20216-20223, 2021.
10. Li D and Liu C. Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease. Nat Chem Biol 17: 237-245, 2021.
11. Li T, Yin Y, Zhou Z, Qiu J, Liu W, Zhang X, He K, Cai Y, Zhu ZJ. Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain. Nat Commun 12: 4343, 2021.
12. Lou MM, Tang XQ, Wang GM, He J, Luo F, Guan MF, Wang F, Zou H, Wang JY, Zhang Q, Xu MJ, Shi QL, Shen LB, Ma GM, Wu Y, Zhang YY, Liang AB, Wang TH, Xiong LL, Wang J, Xu J, Wang WY. Long noncoding RNA BS-DRL1 modulates the DNA damage response and genome stability by interacting with HMGB1 in neurons. Nat Commun 12: 4075, 2021.
13. Mei X, Guo Y, Xie Z, Zhong Y, Wu X, Xu D, Li Y, Liu N, Zhu ZJ. RIPK1 regulates starvation resistance by modulating aspartate catabolism. Nat Commun 12: 6144, 2021.
14. Sun Y, Long H, Xia W, Wang K, Zhang X, Sun B, Cao Q, Zhang Y, Dai B, Li D, Liu C. The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type alpha-synuclein. Nat Commun 12: 6252, 2021.
15. Wang H, Qi W, Zou C, Xie Z, Zhang M, Naito MG, Mifflin L, Liu Z, Najafov A, Pan H, Shan B, Li Y, Zhu ZJ, Yuan J.NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation. Nat Commun 12: 4826, 2021.
16. Wang LQ, Zhao K, Yuan HY, Li XN, Dang HB, Ma Y, Wang Q, Wang C, Sun Y, Chen J, Li D, Zhang D, Yin P, Liu C, Liang Y. Genetic prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM. Sci Adv 7: eabg9676, 2021.
17. Zhang S, Liu YQ, Jia C, Lim YJ, Feng G, Xu E, Long H, Kimura Y, Tao Y, Zhao C, Wang C, Liu Z, Hu JJ, Ma MR, Liu Z, Jiang L, Li D, Wang R, Dawson VL, Dawson TM, Li YM, Mao X, Liu C. Mechanistic basis for receptor-mediated pathological alpha-synuclein fibril cell-to-cell transmission in Parkinson's disease. Proc Natl Acad Sci U S A 118: 2021.
18. Wu X, Ma Y, Zhao K, Zhang J, Sun Y, Li Y, Dong X, Hu H, Liu J, Wang J, Zhang X, Li B, Wang H, Li D, Sun B, Lu J, Liu C. The structure of a minimum amyloid fibril core formed by necroptosis-mediating RHIM of human RIPK3. Proc Natl Acad Sci U S A 118: 2021.
19. Long H, Zheng W, Liu Y, Sun Y, Zhao K, Liu Z, Xia W, Lv S, Liu Z, Li D, He KW, Liu C. Wild-type alpha-synuclein inherits the structure and exacerbated neuropathology of E46K mutant fibril strain by cross-seeding. Proc Natl Acad Sci U S A 118: 2021.
20. Liang W, Qi W, Geng Y, Wang L, Zhao J, Zhu K, Wu G, Zhang Z, Pan H, Qian L, Yuan J. Necroptosis activates UPR sensors without disrupting their binding with GRP78. Proc Natl Acad Sci U S A 118: 2021.
21. Meng H, Wu G, Zhao X, Wang A, Li D, Tong Y, Jin T, Cao Y, Shan B, Hu S, Li Y, Pan L, Tian X, Wu P, Peng C, Yuan J, Li G, Tan L, Wang Z, Li Y. Discovery of a cooperative mode of inhibiting RIPK1 kinase. Cell Discov 7: 41, 2021.
22. Huang X, Tan S, Li Y, Cao S, Li X, Pan H, Shan B, Qian L, Yuan J. Caspase inhibition prolongs inflammation by promoting a signaling complex with activated RIPK1. J Cell Biol 220: 2021.
23. Shen X, Wang C, Liang N, Liu Z, Li X, Zhu ZJ, Merriman TR, Dalbeth N, Terkeltaub R, Li C, Yin H. Serum Metabolomics Identifies Dysregulated Pathways and Potential Metabolic Biomarkers for Hyperuricemia and Gout. Arthritis Rheumatol 73: 1738-1748, 2021.
24. Zu R, Yu Z, Zhao J, Lu X, Liang W, Sun L, Si C, Zhu K, Zhang T, Li G, Zhang M, Zhang Y, Liu N, Yuan J, Shan B. Quantitative analysis of phosphoproteome in necroptosis reveals a role of TRIM28 phosphorylation in promoting necroptosis-induced cytokine production. Cell Death Dis 12: 994, 2021.
25. Sun L, Yan Y, Lv H, Li J, Wang Z, Wang K, Wang L, Li Y, Jiang H, Zhang Y. Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth. Cell Chem Biol 2021.
26. Shan H, Liu J, Shen J, Dai J, Xu G, Lu K, Han C, Wang Y, Xu X, Tong Y, Xiang H, Ai Z, Zhuang G, Hu J, Zhang Z, Li Y, Pan L, Tan L. Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chem Biol 28: 855-865 e859, 2021.
27. Qiu J, Li T and Zhu ZJ. Multi-dimensional characterization and identification of sterols in untargeted LC-MS analysis using all ion fragmentation technology. Anal Chim Acta 1142: 108-117, 2021.
28. Tao Y, Xie J, Zhong Q, Wang Y, Zhang S, Luo F, Wen F, Xie J, Zhao J, Sun X, Long H, Ma J, Zhang Q, Long J, Fang X, Lu Y, Li D, Li M, Zhu J, Sun B, Li G, Diao J, Liu C. A novel partially open state of SHP2 points to a "multiple gear" regulation mechanism. J Biol Chem 296: 100538, 2021.
29. Zhang K, Wang Q, Liang Y, Yan Y, Wang H, Cao X, Shan B, Zhang Y, Li A, Fang Y. Quantitative Proteomic Analysis of Mouse Sciatic Nerve Reveals Post-injury Upregulation of ADP-Dependent Glucokinase Promoting Macrophage Phagocytosis. Front Mol Neurosci 14: 777621, 2021.
30. Zhang L, Wang Z, Wang Z, Luo F, Guan M, Xu M, Li Y, Zhang Y, Wang Z, Wang W. A Simple and Efficient Method to Generate Dual Site-Specific Conjugation ADCs with Cysteine Residue and an Unnatural Amino Acid. Bioconjug Chem 32: 1094-1104, 2021.
31. Deng K, Zhao F, Rong Z, Cao L, Zhang L, Li K, Hou Y, Zhu ZJ. WaveICA 2.0: a novel batch effect removal method for untargeted metabolomics data without using batch information. Metabolomics 17: 87, 2021.
32. Wang H, Zhang Y, Zeng K, Qiang J, Cao Y, Li Y, Fang Y, Zhang Y, Chen Y. Selective Mitochondrial Protein Labeling Enabled by Biocompatible Photocatalytic Reactions inside Live Cells. JACS Au 1: 1066-1075, 2021.
33. Lv J, Wang J, Shen X, Liu J, Zhao D, Wei M, Li X, Fan B, Sun Y, Xue F, Zhu ZJ, Zhang T. A serum metabolomics analysis reveals a panel of screening metabolic biomarkers for esophageal squamous cell carcinoma. Clin Transl Med 11: e419, 2021.
