2022：
(1-55)
1. Li W, Shan B, Zou C, Wang H, Zhang MM, Zhu H, Naito MG, Xu D, Manuel VJ, Mifflin L, Hou Z, Ravits J, Yuan J. Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response. Cell Res 32: 621-637, 2022.
2. Fan Y, Zhao Q, Xia W, Tao Y, Yu W, Chen M, Liu Y, Zhao J, Shen Y, Sun Y, Si C, Zhang S, Zhang Y, Li W, Liu C, Wang J, Li D. Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. Cell Res 32: 585-588, 2022.
3. Li D and Liu C. Conformational strains of pathogenic amyloid proteins in neurodegenerative diseases. Nat Rev Neurosci 23: 523-534, 2022.
4. Lu S, Hu J, Arogundade OA, Goginashvili A, Vazquez-Sanchez S, Diedrich JK, Gu J, Blum J, Oung S, Ye Q, Yu H, Ravits J, Liu C, Yates JR, 3rd, Cleveland DW. Heat-shock chaperone HSPB1 regulates cytoplasmic TDP-43 phase separation and liquid-to-gel transition. Nat Cell Biol 24: 1378-1393, 2022
5. Qi W and Yuan J. RIPK1 and RIPK3 form mosaic necrosomes. Nat Cell Biol 24: 406-407, 2022.
6. Li D and Liu C. Spatiotemporal dynamic regulation of membraneless organelles by chaperone networks. Trends Cell Biol 32: 1-3, 2022
7. Wang L, Li J, Wang Q, Ge MX, Ji J, Liu D, Wang Z, Cao Y, Zhang Y, Zhang ZR. TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation. Mol Cell 82: 3453-3467 e3414, 2022.
8. Guo L, Zhao Y, Zhang Q, Feng Y, Bi L, Zhang X, Wang T, Liu C, Ma H, Sun B. Stochastically multimerized ParB orchestrates DNA assembly as unveiled by single-molecule analysis. Nucleic Acids Res 50: 9294-9305, 2022.
9. Niu K, Zhang J, Ge S, Li D, Sun K, You Y, Qiu J, Wang K, Wang X, Liu R, Liu Y, Li B, Zhu ZJ, Qu L, Jiang H, Liu N. ONE-seq: epitranscriptome and gene-specific profiling of NAD-capped RNA. Nucleic Acids Res 2022.
10. Tao Y, Sun Y, Lv S, Xia W, Zhao K, Xu Q, Zhao Q, He L, Le W, Wang Y, Liu C, Li D. Heparin induces alpha-synuclein to form new fibril polymorphs with attenuated neuropathology. Nat Commun 13: 4226, 2022.
11. Li Y, Lu S, Gu J, Xia W, Zhang S, Zhang S, Wang Y, Zhang C, Sun Y, Lei J, Liu C, Su Z, Yang J, Peng X, Li D. SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation. Protein Cell 13: 602-614, 2022.
12. Wang LQ, Ma Y, Yuan HY, Zhao K, Zhang MY, Wang Q, Huang X, Xu WC, Dai B, Chen J, Li D, Zhang D, Wang Z, Zou L, Yin P, Liu C, Liang Y. Cryo-EM structure of an amyloid fibril formed by full-length human SOD1 reveals its conformational conversion. Nat Commun 13: 3491, 2022.
13. Zhou Z, Luo M, Zhang H, Yin Y, Cai Y, Zhu ZJ. Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking. Nat Commun 13: 6656, 2022.
14. Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, Liu N, Gu J, Xu D. SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation. Nat Commun 13: 7153, 2022.
15. Wang H, Jia H, Gao Y, Zhang H, Fan J, Zhang L, Ren F, Yin Y, Cai Y, Zhu J, Zhu ZJ. Serum metabolic traits reveal therapeutic toxicities and responses of neoadjuvant chemoradiotherapy in patients with rectal cancer. Nat Commun 13: 7802, 2022.
16. He H, Yang W, Su N, Zhang C, Dai J, Han F, Singhal M, Bai W, Zhu X, Zhu J, Liu Z, Xia W, Liu X, Zhang C, Jiang K, Huang W, Chen D, Wang Z, He X, Kirchhoff F, Li Z, Liu C, Huan J, Wang X, Wei W, Wang J, Augustin HG, Hu J. Activating NO-sGC crosstalk in the mouse vascular niche promotes vascular integrity and mitigates acute lung injury. J Exp Med 220: 2023.
17. Wang R, Yin Y, Li J, Wang H, Lv W, Gao Y, Wang T, Zhong Y, Zhou Z, Cai Y, Su X, Liu N, Zhu ZJ. Global stable-isotope tracing metabolomics reveals system-wide metabolic alternations in aging Drosophila. Nat Commun 13: 3518, 2022.
18. Wang T, Hu J, Li Y, Bi L, Guo L, Jia X, Zhang X, Li D, Hou XM, Modesti M, Xi XG, Liu C, Sun B. Bloom Syndrome Helicase Compresses Single-Stranded DNA into Phase-Separated Condensates. Angew Chem Int Ed Engl 61: e202209463, 2022.
19. Sun Z, Ye J and Yuan J. PINK1 mediates neuronal survival in monkey. Protein Cell 13: 4-5, 2022.
20. Wang JY, Ma GM, Tang XQ, Shi QL, Yu MC, Lou MM, He KW, Wang WY. Brain region-specific synaptic function of FUS underlies the FTLD-linked behavioural disinhibition. Brain 2022.
21. Cai Y, Zhou Z, Zhu Z-J. Advanced analytical and informatic strategies for metabolite annotation in untargeted metabolomics.Trends in Analytical Chemistry 158:116903
22. Zong FJ, Min X, Zhang Y, Li YK, Zhang XT, Liu Y, He KW. Circadian time- and sleep-dependent modulation of cortical parvalbumin-positive inhibitory neurons. EMBO J e111304, 2022.
23. Zhu S, Gu J, Yao J, Li Y, Zhang Z, Xia W, Wang Z, Gui X, Li L, Li D, Zhang H, Liu C. Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis. Dev Cell 57: 583-597 e586, 2022.
24. Cheng L, Zhou S, Zhou S, Shi K, Cheng Y, Cai MC, Ye K, Lin L, Zhang Z, Jia C, Xiang H, Zang J, Zhang M, Yin X, Li Y, Di W, Zhuang G, Tan L. Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer. Cancer Res 82: 3588-3602, 2022.
25. Wang Q, Li Z, Zhang S, Li Y, Wang Y, Fang Z, Ma Y, Liu Z, Zhang W, Li D, Liu C, Ye M. Global profiling of arginine dimethylation in regulating protein phase separation by a steric effect-based chemical-enrichment method. Proc Natl Acad Sci U S A 119: e2205255119, 2022.
26. Dong K, Wei R, Jin T, Zhang M, Shen J, Xiang H, Shan B, Yuan J, Li Y. HOIP modulates the stability of GPx4 by linear ubiquitination. Proc Natl Acad Sci U S A 119: e2214227119, 2022.
27. Song Y, Dai B, Wang Y, Wang Y, Liu C, Gourdon P, Liu L, Wang K, Dong M. Identifying Heterozipper beta-Sheet in Twisted Amyloid Aggregation. Nano Lett 22: 3707-3712, 2022.
28. Zhang C, He H, Dai J, Li Y, He J, Yang W, Dai J, Han F, Kong W, Wang X, Zheng X, Zhou J, Pan W, Chen Z, Singhal M, Zhang Y, Guo F, Hu J. KANK4 Promotes Arteriogenesis by Potentiating VEGFR2 Signaling in a TALIN-1-Dependent Manner. Arterioscler Thromb Vasc Biol 42: 772-788, 2022.
29. Hou Y, Lu H, Li J, Guan Z, Zhang J, Zhang W, Yin C, Sun L, Zhang Y, Jiang H. A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2'3'-cGAMP. Cell Chem Biol 29: 133-144 e120, 2022.
30. Li J, Xie J, Godec A, Weninger KR, Liu C, Smith JC, Hong L. Non-ergodicity of a globular protein extending beyond its functional timescale. Chem Sci 13: 9668-9677, 2022.
31. Zhou J, Geng Y, Su T, Wang Q, Ren Y, Zhao J, Fu C, Weber M, Lin H, Kaminker JS, Liu N, Sheng M, Chen Y. NMDA receptor-dependent prostaglandin-endoperoxide synthase 2 induction in neurons promotes glial proliferation during brain development and injury. Cell Rep 38: 110557, 2022.
32. Long H, Zhang S, Zeng S, Tong Y, Liu J, Liu C, Li D. Interaction of RAGE with alpha-synuclein fibrils mediates inflammatory response of microglia. Cell Rep 40: 111401, 2022.
33. Gao C, Gu J, Zhang H, Jiang K, Tang L, Liu R, Zhang L, Zhang P, Liu C, Dai B, Song J. Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus. Cell Rep 40: 111086, 2022.
34. Sun L, Yan Y, Lv H, Li J, Wang Z, Wang K, Wang L, Li Y, Jiang H, Zhang Y. Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth. Cell Chem Biol 29: 373-385 e376, 2022.
35. Lin L, Shi K, Zhou S, Cai MC, Zhang C, Sun Y, Zang J, Cheng L, Ye K, Ma P, Shen P, Zhang M, Cheng Y, Qi C, Li Y, Yin X, Zheng Y, Tan L, Zhuang G, Zang R. SOX17 and PAX8 constitute an actionable lineage-survival transcriptional complex in ovarian cancer. Oncogene 41: 1767-1779, 2022.
36. Zhang S, Zhu Y, Lu J, Liu Z, Lobato AG, Zeng W, Liu J, Qiang J, Zeng S, Zhang Y, Liu C, Liu J, He Z, Zhai RG, Li D. Specific binding of Hsp27 and phosphorylated Tau mitigates abnormal Tau aggregation-induced pathology. Elife 11: 2022.
37. Deng X, Sun X, Yue W, Duan Y, Hu R, Zhang K, Ni J, Cui J, Wang Q, Chen Y, Li A, Fang Y. CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1. J Cell Biol 221: 2022.
38. Tan L, Shan H, Han C, Zhang Z, Shen J, Zhang X, Xiang H, Lu K, Qi C, Li Y, Zhuang G, Chen G, Tan L. Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer. J Med Chem 65: 13645-13659, 2022.
39. Liu W, Zhang WD, Li T, Zhou Z, Luo M, Chen X, Cai Y, Zhu ZJ. Four-Dimensional Untargeted Profiling of N-Acylethanolamine Lipids in the Mouse Brain Using Ion Mobility-Mass Spectrometry. Anal Chem 94: 12472-12480, 2022.
40. Li Y, Gu J, Liu C and Li D. A high-throughput method for exploring the parameter space of protein liquid-liquid phase separation.Cell Reports Physical Science,2022.
41. Li J, Cao Y, Niu K, Qiu J, Wang H, You Y, Li D, Luo Y, Zhu Z, Zhang Y, Liu N. Quantitative Acetylomics Reveals Dynamics of Protein Lysine Acetylation in Mouse Livers During Aging and Upon the Treatment of Nicotinamide Mononucleotide. Mol Cell Proteomics 21: 100276, 2022.
42. Chen X, Yin Y, Luo M, Zhou Z, Cai Y, Zhu ZJ. Trapped ion mobility spectrometry-mass spectrometry improves the coverage and accuracy of four-dimensional untargeted lipidomics. Anal Chim Acta 1210: 339886, 2022.
43. Zhao Q, Tao Y, Zhao K, Ma Y, Xu Q, Liu C, Zhang S, Li D. Structural Insights of Fe(3+) Induced alpha-synuclein Fibrillation in Parkinson's Disease. J Mol Biol 435: 167680, 2023.
44. Li Y, Gu J, Wang C, Hu J, Zhang S, Liu C, Zhang S, Fang Y, Li D. Hsp70 exhibits a liquid-liquid phase separation ability and chaperones condensed FUS against amyloid aggregation. iScience 25: 104356, 2022.
45. Sun Y, Zhang S, Hu J, Tao Y, Xia W, Gu J, Li Y, Cao Q, Li D, Liu C. Molecular structure of an amyloid fibril formed by FUS low-complexity domain. iScience 25: 103701, 2022.
46. Ren J, Wang X, Dong C, Wang G, Zhang W, Cai C, Qian M, Yang D, Ling B, Ning K, Mao Z, Liu B, Wang T, Xiong L, Wang W, Liang A, Gao Z, Xu J. Sirt1 Protects Subventricular Zone-Derived Neural Stem Cells from DNA Double-Strand Breaks and Contributes to Olfactory Function Maintenance in Aging Mice. Stem Cells 40: 493-507, 2022.
47. Huang C, Lu J, Ma X, Qiang J, Wang C, Liu C, Fang Y, Zhang Y, Jiang L, Li D, Zhang S. The mouse nicotinamide mononucleotide adenylyltransferase chaperones diverse pathological amyloid client proteins. J Biol Chem 298: 101912, 2022.
48. Chen C, Lou MM, Sun YM, Luo F, Liu FT, Luo SS, Wang WY, Wang J. Serum metabolomic characterization of PLA2G6-associated dystonia-parkinsonism: A case-control biomarker study. Front Neurosci 16: 879548, 2022.
49. Zou H, Wang JY, Ma GM, Xu MM, Luo F, Zhang L, Wang WY. The function of FUS in neurodevelopment revealed by the brain and spinal cord organoids. Mol Cell Neurosci 123: 103771, 2022.
50. Wu X, Niu K, Wang X, Zhao J, Wang H, Li D, Wang H, Miao T, Yang Y, Ma H, Zhang Y, Pan L, Liu R, Bai H, Liu N. microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-beta pathway in Drosophila. Genetics 220: 2022.
51. Liang W and Yuan J. Visualizing Endogenous Necrosomes in Necrosomes by In Situ Proximity Ligation Assay. Curr Protoc 2: e388, 2022.
52. Yang Y, Li X, Zhang T, Xu D. RIP kinases and necroptosis in aging and aging-related diseases.Life Medicine.2022.
53. Zhang S, Dong H, Bian J, Li D, Liu C. Targeting amyloid proteins for clinical diagnosis of neurodegenerative diseases. Fundamental Research,2022.
54. Hou Y, Lu H, Sun L, Zhang Y, Jiang H. Protocol for identification and validation of 2'3'-cGAMP-binding proteins by photoaffinity probes. STAR Protoc 3: 101076, 2022.
55. Long H, Zeng S, Sun Y, Liu C.,Biochemical and biophysical characterization of pathological aggregation of amyloid proteins.Biophysics Reports, 2022
